Users:
Journal: Home » Archive » Issue » View Article  
Journal
Journal Info
Journal Online
For Authors
Instructions for Authors
Subscription

Biotechnology & Biotechnological Equipment

Subject: Biotechnology
Publisher: Diagnosis Press
ISSN 1310-2818

Volume 26, Number 1
Date: February 2012
DOI: 10.5504/bbeq.2011.0156

  PDF (1742 KB)

ANTIBACTERIAL AND ANTITUMOR ACTIVITIES OF SOME WILD FRUITS GROWN IN TURKEY

Arzu Ucar Turker, Arzu Birinci Yildirim and Fatma Pehlivan Karakas

Abant Izzet Baysal University, Department of Biology, Bolu, Turkey

Abstract

Two different bioassays (antibacterial and antitumor) were performed to show the biological activities of eight different wild fruits [Viburnum opulus L. (guelder rose), Viburnum lantana L. (wayfaring tree), Cornus mas L. (cornelian cherry), Pyracantha coccinea Roemer (firethorn), Rubus caesius L. (dewberry), Crataegus tanacetifolia (Lam.) Pers (tansy-leaved thorn), Crataegus monogyna Jacq. (hawthorn) and Rosa canina L. (dog rose)] grown in Turkey. For each fruit, 8 different extracts (aqueous and ethanol extracts prepared from hot and cold treatments of fresh and dried fruits) were obtained and a total of 64 extracts were evaluated. The disc diffusion assay (Kirby-Bauer Method) was used to screen for antibacterial activity. Among the tested fruits, best antibacterial activity was obtained with fresh fruits of wayfaring tree, firethorn and hawthorn. Hot ethanol extracts of these fruits showed strong antibacterial activity against S. aureus, S. epidermidis and S. pyogenes. Antitumor activity was evaluated with potato disc tumor induction assay. Best antitumor activity was obtained with cold water extract of fresh fruits of R. caesius (100% inhibition). Cold or hot ethanol extracts of fresh V. lantana fruits (90.5% and 95.2%, respectively), cold water extract of fresh C. monogyna fruits (85.7%) and hot ethanol extracts of fresh C. tanacetifolia fruits (71.4%) also exhibited strong tumor inhibition.

References

  1. Altun M.L., Citoglu G.S., Yilmaz B.S., Ozbek H. (2009) Pharm. Biol., 47, 653-658.
  2. Altun M.L., Citoğlu G.S., Yilmaz B.S., Coban T. (2008) Int. J. Food Sci. Nutr., 59, 175-80.
  3. Andrews J.M. (2004) J. Antimicrob. Chemother., 53, 713-728.
  4. Bagchi D., Sen C.K., Bagchi M., Atalay M. (2004) Biochem.-Moscow, 69, 75.
  5. Barros L., Carvalho A.M., Ferreira I.C.F.R. (2011) Phytochem. Analysis, 22, 181-188.
  6. Barry A.L., Thornsberry C. (1985) In: Manual of Clinical Microbiology (E.H. Lennette, Ed.), American Association for Microbiology, Washington D.C., 978-987.
  7. Baytop T. (1999) Türkiye’de Bitkiler ile Tedavi, Nobel Tıp Kitabevleri.
  8. Benli M., Yigit N., Geven F., Guney K., Bingol U. (2008) Cell Biochem., 26, 844-851.
  9. Bernatoniene J., Masteikova R., Majiene D., Savickas A., Kevelaitis E., Bernatoniene R., Dvorackova K., Civinskiene G., Lekas R., Vitkevicius K., Peciura R. (2008) Med. Lit., 44, 706-712.
  10. Cekic C., Ozgen M. (2010) J. Food Comp. Anal., 23, 540-544.
  11. Chevallier A. (1996) The Encyclopedia of Medicinal Plants, Darling Kindersley Limited, London.
  12. Chrubasik C., Roufogalis B.D., Muller-Ladner U., Chrubasik S. (2008) Phytother. Res., 22, 725-733.
  13. Coker P.S., Rodecke J., Guy C., Camper N.D. (2003) Phytomed., 10, 133-138.
  14. Dai J., Patel J.D., Mumper R.J. (2007) J. Med. Food, 10, 258-265.
  15. Davis P.H. (1972) Flora of Turkey and the East Aegean Islands, Vol. 4, Edinburgh Univ. Press, Edinburgh.
  16. Dulger B., Gonuz A. (2004) Pakistan J. Biol. Sci., 7, 1559-1562.
  17. Ersoy N., Bagci Y., Gok V. (2011) Sci. Res. Essays, 6, 98-102.
  18. Ferrigini N.R., Putnam J.E., Anderson B., Jacobsen L.B., Nichols D.E., Moore D.S., McLaughlin J.L. (1982) J. Nat. Prod., 45, 679-686.
  19. Galsky A.G., Wilsey T.P., Powell R.G. (1980) Plant Physiol., 65, 184-185.
  20. Ghisalberti E.L. (1993) In: Bioactive Natural Products, Detection, Isolation and Structural Determination (S.M. Colegate, R.J. Molyneux, Eds.), CRC Press, 9-49.
  21. Glogowski W., Galsky A.G. (1978) Plant Physiol., 61, 1031-1033.
  22. Grieve M. (1982) A Modern Herbal, Vol I and II, Dover Publications, Inc., New York.
  23. Gulcin I., Beydemir S., Sat I.G., Kufrevioglu O.I. (2005) Acta Aliment., 34, 193-202.
  24. Guven K., Yucel E., Cetintas F. (2006) Pharm. Biol., 44, 79-83.
  25. Hashempour A., Ghazvini R.F., Bakhshi D., Ghasemnezhad M., Sharafti M., Ahmadian H. (2010) Hort. Environ. Biotechnol., 51, 83-88.
  26. Hosseinimehr S.J., Azadbakht M., Abadi A.J. (2008) Environ. Toxicol. Phar., 25, 51-56.
  27. Johnson J.L, Boniser J.A., Scheerens J.C., Giusti M.M. (2011) J. Agr. Food Chem., 59, 1638-1645.
  28. Kao E.S., Wang C.J., Lin W.L., Chu C.Y., Tseng T.H. (2007) Food Chem. Toxicol., 45, 1795-1804.
  29. Kilicgun H., Altiner D. (2010) Pharmacogn. Mag., 6, 238-241.
  30. Krisch J., Galgoczy L., Tolgyesi M., Papp T., Vagvolgyi C. (2008) Acta Biol. Szegediensis, 52, 267-270.
  31. Kumarasamy Y., Cox P.J., Jaspars M., Nahar L., Sarker S.D. (2002) J. Ethnopharmacol., 83, 73-77.
  32. Kumarasamy Y., Cox P.J., Jaspars M., Rashid M.A., Sarker S.D. (2003) Pharm. Biol., 41, 237-242.
  33. Larsen E., Christensen L.P. (2007) J. Food Lipids, 14, 272-279.
  34. Laux M.T., Aregullin M., Rodriguez E. (2007) Nat. Prod. Com., 2, 1015-1018.
  35. Lippincott B.B., Lippincott J.A. (1969) J. Bacteriol., 2, 620-628.
  36. Mamedov N., Craker L.E. (2004) Acta Hortic., 629, 83-86.
  37. McLaughlin J.L. (1991) In: Methods in Plant Biochemistry (K. Hostetsman, Ed.), Academic Press, London, 1-31.
  38. McLaughlin J.L., Chang C.J., Smith D.L. (1993) In: Human Medicinal Agents from Plants (A.D. Kinghorn, M.F. Baladrin, Eds.), ACS Symposium Series 534, Washington DC, 112-137.
  39. McLaughlin J.L., Rogers L.L., Anderson J.E. (1998) Drug Inf. J., 32, 513-524.
  40. Min B.S., Kim Y.H., Lee S.M., Jung H.J., Lee J.S., Na M.K., Lee C.O., Lee J.P., Bae K. (2000) Arch. Pharm. Res., 23, 155-158.
  41. Milivojevic J., Maksimovic V., Nikolic M., Bogdanovic J., Maletic R., Milatovic D. (2011) J. Food Quality, 34, 1-9.
  42. Orhan N., Aslan M., Hosbas S., Orhan D.D. (2009) Pharmacogn. Mag., 5, 309-315.
  43. Oskay M., Sari D. (2007) Pharm. Biol., 45, 176-181.
  44. Ozcan M. (2000) Acta Aliment, 29, 377-384.
  45. Pantelidis G.E., Vasilakakis M., Manganaris G.A., Diamantidis G. (2007) Food Chem., 102, 777-783.
  46. Proestos C., Boziaris I.S., Kapsokefalou M., Komaitis M. (2008) Food Technol. Biotechnol., 46, 151-156.
  47. Raskin I., Ribnicky D.M., Komarnytsky S., Ilic N., Poulev A., Borisjuk N., Brinker A., Moreno D.A., Ripoll C., Yakoby N., O’Neal J.M., Cornwell T., Pastor I., Fridlender B. (2002) Trends Biotechnol., 20, 522-531.
  48. Rauha J.P., Remes S., Heinonen M., Hopia A., Kahkonen M., Kujala T., Pihlaja K., Vuorela H., Vuorela P. (2000) Int. J. Food Microbiol., 56, 3-12.
  49. Rios J.L., Recio M.C. (2005) J. Ethnopharmacol., 100, 80-84.
  50. Rop O., Reznicek V., Valsikova M., Jurikova T., Mlcek J., Kramarova D. (2010) Molecules, 15, 4467-4477.
  51. Saenz M.T., Ahumada M.C., Garcia M.D. (1997) Z. Naturforsch. C., 52, 42-44.
  52. Sagdic O., Aksoy A., Ozkan G. (2006) Acta Aliment., 35, 487-492.
  53. Savikin K., Zdunic G., Jankovic T., Stanojkovic T., Juranic Z., Menkovic N. (2009) Nat. Prod. Res., 23, 1731-1739.
  54. Seeram N.P., Adams L.S., Zhang Y.J., Lee R., Sand D., Scheuller H.S., Heber D. (2006) J. Agr. Food Chem., 54, 9329-9339.
  55. Seeram N.P. (2008) J. Agr. Food Chem., 56, 630-635.
  56. Serteser A., Kargioglu M., Gok V., Baci Y., Ozcan M.M., Arslan D. (2008) Int. J. Food Sci. Nutr., 59, 643-651.
  57. Stoner G.D., Chen T., Kresty L.A., Aziz R.M., Reinemann T., Nines R. (2006) Nutr. Cancer, 54, 33-46,
  58. Tadic V.M., Dobric S., Markovic G.M., Orevic S.M., Arsic I.A., Menkovic N.R., Stevic T. (2008) J. Agr. Food Chem., 56, 7700-7709.
  59. Tural S., Koca I. (2008) Sci. Hortic., 116, 362-366.
  60. Turker A., Usta C. (2006) Biotechnol. Biotech. Eq., 20, 105-113.
  61. Tuzlaci E., Aymaz P.E. (2001) Fitoterapia, 72, 323-343.
  62. Yilmaz N., Yayli N., Misir G., Coskuncelebi K., Karaoglu S., Yayli N. (2008) Asian J. Chem., 20, 3324-3330.
  63. Yilmaz B. S, Citoglu G. S, Altun M. L., Ozbek H. (2007) Pharm. Biol, 45, 241-245.
 


Journal Home | Privacy Statement | Terms and Conditions | Contact Info | Feed Back
© Copyright Diagnosis Press 2004 Web design: CMC Bulgaria Ltd.