Biotechnology & Biotechnological Equipment

Volume 22, Number 4
Date: 2008

KNOWLEDGE-BASED APPROACH TO CONTROL OF MIXED CULTURE CULTIVATION FOR PHB PRODUCTION PROCESS

P. Koprinkova-Hristova

Abstract

The present paper considers the control problems of the mixed culture system where sugars were converted to lactate by the microorganism Lactobacillus delbrueckii and then the lactate was converted to poly-β-hydroxybutyrate (PHB) by the microorganism Ralstonia euthropha. Fuzzy rule base that combines all the experts’ knowledge about the process control is developed. It is shown that the used intelligent approach outperforms the classical control strategies applied before.